Interleukin 10 knockout frail mice develop cardiac and vascular dysfunction with increased age()

Cardiovascular dysfunction is a primary independent predictor of age-related morbidity and mortality. Frailty is associated with activation of inflammatory pathways and fatigue that commonly presents and progresses with age. Interleukin 10 (IL-10), the cytokine synthesis inhibitory factor, is an ant...

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Hlavní autoři: Sikka, Gautam, Miller, Karen L., Steppan, Jochen, Pandey, Deepesh, Jung, Sung M., Fraser, Charles D., Ellis, Carla, Ross, Daniel, Vandegaer, Koenraad, Bedja, Djahida, Gabrielson, Kathleen, Walston, Jeremy D., Berkowitz, Dan E., Barouch, Lili A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744178/
https://ncbi.nlm.nih.gov/pubmed/23159957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2012.11.001
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