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Cardioprotective Effect of Beta-3 Adrenergic Receptor Agonism: Role of Neuronal Nitric Oxide Synthase: Beta3-AR prevents cardiac dysfunction through nNOS

OBJECTIVE: The aim of this study is to determine if activation of β3-adrenoceptor (β3-AR) and downstream signaling of NOS isoforms protects the heart from failure and hypertrophy induced by pressure overload. BACKGROUND: β3-AR and its downstream signaling pathways are recognized as novel modulators...

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Detalhes bibliográficos
Main Authors: Niu, Xiaolin, Watts, Vabren L., Cingolani, Oscar H., Sivakumaran, Vidhya, Leyton-Mange, Jordan S., Ellis, Carla L., Miller, Karen L., Vandegaer, Konrad, Bedja, Djahida, Gabrielson, Kathleen L., Paolocci, Nazareno, Kass, David A., Barouch, Lili A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366593/
https://ncbi.nlm.nih.gov/pubmed/22624839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2011.12.046
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