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S-Nitrosation of arginase 1 requires direct interaction with inducible nitric oxide synthase

Arginase constrains endothelial nitric oxide synthase activity by competing for the common substrate, L-Arginine. We have recently shown that inducible nitric oxide synthase (NOS2) S-nitrosates and activates arginase 1 (Arg1) leading to age-associated vascular dysfunction. Here, we demonstrate that...

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Huvudupphovsmän: Dunn, Jessilyn, Gutbrod, Sarah, Webb, Alanah, Pak, Alina, Jandu, Simran K., Bhunia, Anil, Berkowitz, Dan E., Santhanam, Lakshmi
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744166/
https://ncbi.nlm.nih.gov/pubmed/21533769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-011-0841-2
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