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S-Nitrosation of arginase 1 requires direct interaction with inducible nitric oxide synthase
Arginase constrains endothelial nitric oxide synthase activity by competing for the common substrate, L-Arginine. We have recently shown that inducible nitric oxide synthase (NOS2) S-nitrosates and activates arginase 1 (Arg1) leading to age-associated vascular dysfunction. Here, we demonstrate that...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3744166/ https://ncbi.nlm.nih.gov/pubmed/21533769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-011-0841-2 |
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