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The Role of Nogo and the Mitochondria–Endoplasmic Reticulum Unit in Pulmonary Hypertension

Pulmonary arterial hypertension (PAH) is caused by excessive proliferation of vascular cells, which occlude the lumen of pulmonary arteries (PAs) and lead to right ventricular failure. The cause of the vascular remodeling in PAH remains unknown, and the prognosis of PAH remains poor. Abnormal mitoch...

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Autores principales: Sutendra, Gopinath, Dromparis, Peter, Wright, Paulette, Bonnet, Sébastien, Haromy, Alois, Hao, Zhengrong, McMurtry, M. Sean, Michalak, Marek, Vance, Jean E., Sessa, William C., Michelakis, Evangelos D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744110/
https://ncbi.nlm.nih.gov/pubmed/21697531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002194
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