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Reaction between peroxynitrite and boronates: EPR spin-trapping, HPLC analyses, and quantum mechanical study of the free radical pathway

Recently we showed that peroxynitrite (ONOO(−)) reacts directly and rapidly with aromatic and aliphatic boronic acids (k ≈ 10(6) M(−1)s(−1)). Product analyses and substrate consumption data indicated that ONOO(−) reacts stoichiometrically with boronates, yielding the corresponding phenols as the maj...

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Detalhes bibliográficos
Main Authors: Sikora, Adam, Zielonka, Jacek, Lopez, Marcos, Dybala-Defratyka, Agnieszka, Joseph, Joy, Marcinek, Andrzej, Kalyanaraman, Balaraman
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743543/
https://ncbi.nlm.nih.gov/pubmed/21434648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100439a
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