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Direct oxidation of boronates by peroxynitrite: Mechanism and implications in fluorescence imaging of peroxynitrite

In this study, we show that boronates, a class of synthetic organic compounds, react rapidly and stoichiometrically with peroxynitrite (ONOO(−)) to form stable hydroxy derivatives as major products. Using stopped-flow kinetic technique, we measured the second order rate constants for the reaction wi...

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Detalhes bibliográficos
Main Authors: Sikora, Adam, Zielonka, Jacek, Lopez, Marcos, Joseph, Joy, Kalyanaraman, B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375817/
https://ncbi.nlm.nih.gov/pubmed/19686842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.08.006
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