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Rapid in vivo assessment of drug efficacy against Mycobacterium tuberculosis using an improved firefly luciferase
OBJECTIVES: In vivo experimentation is costly and time-consuming, and presents a major bottleneck in anti-tuberculosis drug development. Conventional methods rely on the enumeration of bacterial colonies, and it can take up to 4 weeks for Mycobacterium tuberculosis to grow on agar plates. Light prod...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3743513/ https://ncbi.nlm.nih.gov/pubmed/23633686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt155 |
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