A new in vivo model to test anti-tuberculosis drugs using fluorescence imaging

OBJECTIVES: The current method for testing new drugs against tuberculosis in vivo is the enumeration of bacteria in organs by cfu assay. Owing to the slow growth rate of Mycobacterium tuberculosis (Mtb), these assays can take months to complete. Our aim was to develop a more efficient, fluorescence-...

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Detalhes bibliográficos
Main Authors: Zelmer, Andrea, Carroll, Paul, Andreu, Nuria, Hagens, Kristine, Mahlo, Jacqueline, Redinger, Natalja, Robertson, Brian D., Wiles, Siouxsie, Ward, Theresa H., Parish, Tanya, Ripoll, Jorge, Bancroft, Gregory J., Schaible, Ulrich E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394442/
https://ncbi.nlm.nih.gov/pubmed/22635525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dks161
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