A new in vivo model to test anti-tuberculosis drugs using fluorescence imaging

OBJECTIVES: The current method for testing new drugs against tuberculosis in vivo is the enumeration of bacteria in organs by cfu assay. Owing to the slow growth rate of Mycobacterium tuberculosis (Mtb), these assays can take months to complete. Our aim was to develop a more efficient, fluorescence-...

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Hauptverfasser: Zelmer, Andrea, Carroll, Paul, Andreu, Nuria, Hagens, Kristine, Mahlo, Jacqueline, Redinger, Natalja, Robertson, Brian D., Wiles, Siouxsie, Ward, Theresa H., Parish, Tanya, Ripoll, Jorge, Bancroft, Gregory J., Schaible, Ulrich E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394442/
https://ncbi.nlm.nih.gov/pubmed/22635525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dks161
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