Population pharmacokinetics of lopinavir and ritonavir in combination with rifampicin-based antitubercular treatment in HIV-infected children

BACKGROUND: The preferred antiretroviral regimen for young children previously exposed to non-nucleoside reverse transcriptase inhibitors is lopinavir/ritonavir plus two nucleoside reverse transcriptase inhibitors. Rifampicin-based antitubercular treatment reduces lopinavir concentrations. Adding ex...

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Detalhes bibliográficos
Main Authors: Zhang, Chao, Mcllleron, Helen, Ren, Yuan, van der Walt, Jan-Stefan, Karlsson, Mats O, Simonsson, Ulrika SH, Denti, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743021/
https://ncbi.nlm.nih.gov/pubmed/22267466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP1915
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