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ADAM17 mediates Nox4 expression and NADPH oxidase activity in the kidney cortex of OVE26 mice

Matrix protein accumulation is a prominent feature of diabetic nephropathy that contributes to renal fibrosis and decline in renal function. The pathogenic mechanisms of matrix accumulation are incompletely characterized. We investigated if the matrix metalloprotease a disintegrin and metalloproteas...

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Detalhes bibliográficos
Main Authors: Ford, Bridget M., Eid, Assaad A., Göőz, Monika, Barnes, Jeffrey L., Gorin, Yves C., Abboud, Hanna E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742865/
https://ncbi.nlm.nih.gov/pubmed/23678045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00522.2012
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