CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia

Adults with relapsed B-acute lymphoblastic leukemia (ALL) have a dismal prognosis. Only those patients able to achieve a second remission with no minimal residual disease (MRD−) have a hope for long-term survival in the context of a subsequent allogeneic hematopoietic stem cell transplantation (allo...

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Detalhes bibliográficos
Main Authors: Brentjens, Renier, Davila, Marco L, Riviere, Isabelle, Park, Jae, Wang, Xiuyan, Cowell, Lindsay G, Bartido, Shirley, Stefanski, Jolanta, Taylor, Clare, Olszewska, Malgorzata, Borquez-Ojeda, Oriana, Qu, Jinrong, Wasielewska, Teresa, He, Qing, Bernal, Yvette, Rijo, Ivelise V, Hedvat, Cyrus, Kobos, Rachel, Curran, Kevin, Steinherz, Peter, Jurcic, Joseph, Rosenblat, Todd, Maslak, Peter, Frattini, Mark, Sadelain, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742551/
https://ncbi.nlm.nih.gov/pubmed/23515080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005930
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