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Expression and significance of hypoxia-inducible factor-1α and MDR1/P-glycoprotein in laryngeal carcinoma tissue and hypoxic Hep-2 cells

The present study aimed to evaluate the expression of hypoxia-inducible factor-1α (HIF-1α) and MDR1/P-glycoprotein (P-gp) in human laryngeal squamous cell carcinoma (LSCC) tissues, and also to investigate the regulation of MDR1 gene expression by HIF-1α in Hep-2 cells under hypoxic conditions. The e...

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Detalhes bibliográficos
Main Authors: XIE, JIN, LI, DA-WEI, CHEN, XIN-WEI, WANG, FEI, DONG, PIN
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742502/
https://ncbi.nlm.nih.gov/pubmed/23946810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2013.1321
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