The role of metformin and resveratrol in the prevention of hypoxia‐inducible factor 1α accumulation and fibrosis in hypoxic adipose tissue

BACKGROUND AND PURPOSE: Hypoxic activation of hypoxia‐inducible factor 1α (HIF‐1α) and fibrosis in adipose tissue contribute to adipose dysfunction. This study was designed to investigate the effects of metformin and resveratrol on the regulation of HIF‐1α and fibrosis in hypoxic adipose tissue. EXP...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Li, Xiaole, Li, Jia, Wang, Lulu, Li, Aiyun, Qiu, Zhixia, Qi, Lian‐wen, Kou, Junping, Liu, Kang, Liu, Baolin, Huang, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882491/
https://ncbi.nlm.nih.gov/pubmed/27059094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13493
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