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The Sigma Receptor Ligand (+)-Pentazocine Prevents Apoptotic Retinal Ganglion Cell Death induced in vitro by Homocysteine and Glutamate

Recent studies demonstrated that the excitotoxic amino acid homocysteine induces apoptotic death of retinal ganglion cells in vivo. In the present study, an in vitro rat retinal ganglion cell (RGC-5) culture system was used to analyze the toxicity of acute exposure to high levels of homocysteine, th...

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Autori principali: Martin, Pamela Moore, Ola, Mohammad S., Agarwal, Neeraj, Ganapathy, Vadivel, Smith, Sylvia B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742374/
https://ncbi.nlm.nih.gov/pubmed/15046867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbrainres.2003.12.019
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