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The Sigma Receptor Ligand (+)-Pentazocine Prevents Apoptotic Retinal Ganglion Cell Death induced in vitro by Homocysteine and Glutamate

Recent studies demonstrated that the excitotoxic amino acid homocysteine induces apoptotic death of retinal ganglion cells in vivo. In the present study, an in vitro rat retinal ganglion cell (RGC-5) culture system was used to analyze the toxicity of acute exposure to high levels of homocysteine, th...

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Detalhes bibliográficos
Main Authors: Martin, Pamela Moore, Ola, Mohammad S., Agarwal, Neeraj, Ganapathy, Vadivel, Smith, Sylvia B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742374/
https://ncbi.nlm.nih.gov/pubmed/15046867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbrainres.2003.12.019
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