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Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells

Spindle assembly is subject to the regulatory controls of both the cell-cycle machinery and the Ran-signaling pathway. An important question is how the two regulatory pathways communicate with each other to achieve coordinated regulation in mitosis. We show here that Cdc2 kinase phosphorylates the s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, Hoi-Yeung, Zheng, Yixian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC374234/
https://ncbi.nlm.nih.gov/pubmed/15014043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1177304
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