Inhibition of Both EGFR and IGF1R Sensitized Prostate Cancer Cells to Radiation by Synergistic Suppression of DNA Homologous Recombination Repair

Reduced sensitivity of prostate cancer (PC) cells to radiation therapy poses a significant challenge in the clinic. Activation of epidermal growth factor receptor (EGFR), type 1 insulin-like growth factor receptor (IGF1R), and crosstalk between these two signaling pathways have been implicated in th...

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書誌詳細
主要な著者: Wang, Yong, Yuan, Jian Lin, Zhang, Yun Tao, Ma, Jian Jun, Xu, Peng, Shi, Chang Hong, Zhang, Wei, Li, Yu Mei, Fu, Qiang, Zhu, Guang Feng, Xue, Wei, Lei, Yong Hua, Gao, Jing Yu, Wang, Juan Ying, Shao, Chen, Yi, Cheng Gang, Wang, He
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741308/
https://ncbi.nlm.nih.gov/pubmed/23950876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068784
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