Inhibition of Both EGFR and IGF1R Sensitized Prostate Cancer Cells to Radiation by Synergistic Suppression of DNA Homologous Recombination Repair

Reduced sensitivity of prostate cancer (PC) cells to radiation therapy poses a significant challenge in the clinic. Activation of epidermal growth factor receptor (EGFR), type 1 insulin-like growth factor receptor (IGF1R), and crosstalk between these two signaling pathways have been implicated in th...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Wang, Yong, Yuan, Jian Lin, Zhang, Yun Tao, Ma, Jian Jun, Xu, Peng, Shi, Chang Hong, Zhang, Wei, Li, Yu Mei, Fu, Qiang, Zhu, Guang Feng, Xue, Wei, Lei, Yong Hua, Gao, Jing Yu, Wang, Juan Ying, Shao, Chen, Yi, Cheng Gang, Wang, He
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2013
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741308/
https://ncbi.nlm.nih.gov/pubmed/23950876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068784
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