Co-inhibition of EGFR and IGF1R synergistically impacts therapeutically on adrenocortical carcinoma

PURPOSE: Adrenocortical carcinoma (ACC) is a rare tumor with very poor prognosis and no effective treatment. The aim of this study was to explore a novel therapy co-targeting EGFR and IGF1R in vitro and vivo. METHODS: The expression of EGFR and IGF1R were evaluated in a series of adrenocortical tumo...

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Vydáno v:Oncotarget
Hlavní autoři: Xu, Lieyu, Qi, Yicheng, Xu, Yunze, Lian, Jianpo, Wang, Xiaojing, Ning, Guang, Wang, Weiqing, Zhu, Yu
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094996/
https://ncbi.nlm.nih.gov/pubmed/27105537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8827
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