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Metformin Protects Rat Hepatocytes against Bile Acid-Induced Apoptosis
BACKGROUND: Metformin is used in the treatment of Diabetes Mellitus type II and improves liver function in patients with non-alcoholic fatty liver disease (NAFLD). Metformin activates AMP-activated protein kinase (AMPK), the cellular energy sensor that is sensitive to changes in the AMP/ATP-ratio. A...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3741108/ https://ncbi.nlm.nih.gov/pubmed/23951244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071773 |
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