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Metformin protects primary rat hepatocytes against oxidative stress-induced apoptosis

The majority of chronic liver diseases are accompanied by oxidative stress, which induces apoptosis in hepatocytes and liver injury. Recent studies suggest that oxidative stress and insulin resistance are important in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) and the pathophysiolo...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: de la Rosa, Laura Conde, Vrenken, Titia E, Buist-Homan, Manon, Faber, Klaas Nico, Moshage, Han
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448984/
https://ncbi.nlm.nih.gov/pubmed/26038701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.125
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