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Metformin protects primary rat hepatocytes against oxidative stress-induced apoptosis

The majority of chronic liver diseases are accompanied by oxidative stress, which induces apoptosis in hepatocytes and liver injury. Recent studies suggest that oxidative stress and insulin resistance are important in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) and the pathophysiolo...

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書誌詳細
出版年:Pharmacol Res Perspect
主要な著者: de la Rosa, Laura Conde, Vrenken, Titia E, Buist-Homan, Manon, Faber, Klaas Nico, Moshage, Han
フォーマット: Artigo
言語:Inglês
出版事項: BlackWell Publishing Ltd 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448984/
https://ncbi.nlm.nih.gov/pubmed/26038701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.125
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