Hormesis in Cholestatic Liver Disease; Preconditioning with Low Bile Acid Concentrations Protects against Bile Acid-Induced Toxicity

INTRODUCTION: Cholestasis is characterized by accumulation of bile acids and inflammation, causing hepatocellular damage. Still, liver damage markers are highest in acute cholestasis and drop when this condition becomes chronic, indicating that hepatocytes adapt towards the hostile environment. This...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Verhaag, Esther M., Buist-Homan, Manon, Koehorst, Martijn, Groen, Albert K., Moshage, Han, Faber, Klaas Nico
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780766/
https://ncbi.nlm.nih.gov/pubmed/26950211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149782
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