MicroRNAs of the miR-17~92 family are critical regulators of T(FH) differentiation

T follicular helper (T(FH)) cells provide critical help to B cells during humoral immune responses. Here we report that mice with T cell-specific deletion of miR-17~92 family miRNAs (tKO mice) exhibited severely compromised T(FH) differentiation, germinal center formation, antibody responses, and fa...

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Detalhes bibliográficos
Main Authors: Kang, Seung Goo, Liu, Wen-Hsien, Lu, Peiwen, Jin, Hyun Yong, Lim, Hyung W., Shepherd, Jovan, Fremgen, Daniel, Verdin, Eric, Oldstone, Michael B. A., Qi, Hai, Teijaro, John R., Xiao, Changchun
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740954/
https://ncbi.nlm.nih.gov/pubmed/23812097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2648
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