MicroRNAs of the mir-17~92 cluster regulate multiple aspects of pancreatic tumor development and progression

Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy characterized by resistance to currently employed chemotherapeutic approaches. Members of the mir-17~92 cluster of microRNAs (miRNAs) are upregulated in PDAC, but the precise roles of these miRNAs in PDAC are unknown. Using genetically e...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Quattrochi, Brian, Gulvady, Anushree, Driscoll, David R., Sano, Makoto, Klimstra, David S., Turner, Christopher E., Lewis, Brian C.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482626/
https://ncbi.nlm.nih.gov/pubmed/28415794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16277
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