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Cost of rNTP/dNTP pool imbalance at the replication fork
The concentration of ribonucleoside triphosphates (rNTPs) in cells is far greater than the concentration of deoxyribonucleoside triphosphates (dNTPs), and this pool imbalance presents a challenge for DNA polymerases (Pols) to select their proper substrate. This report examines the effect of nucleoti...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740908/ https://ncbi.nlm.nih.gov/pubmed/23882084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309506110 |
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