SOX2–LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors

The transcription factor SRY (sex-determining region)-box 2 (SOX2) is an important functional marker of neural precursor cells (NPCs) and plays a critical role in self-renewal and neuronal differentiation; however, the molecular mechanisms underlying its functions are poorly understood. Using human...

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Bibliographic Details
Main Authors: Cimadamore, Flavio, Amador-Arjona, Alejandro, Chen, Connie, Huang, Chun-Teng, Terskikh, Alexey V.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740872/
https://ncbi.nlm.nih.gov/pubmed/23884650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220176110
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