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SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis
Newborn granule neurons generated from neural progenitor cells (NPCs) in the adult hippocampus play a key role in spatial learning and pattern separation. However, the molecular mechanisms that control activation of their neurogenic program remain poorly understood. Here, we report a novel function...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403144/ https://ncbi.nlm.nih.gov/pubmed/25825708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421480112 |
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