Human ESC-Derived Neural Crest Model Reveals a Key Role for SOX2 in Sensory Neurogenesis

The transcription factor SOX2 is widely known to play a critical role in the central nervous system; however, its role in peripheral neurogenesis remains poorly understood. We recently developed an hESC-based model in which migratory cells undergo epithelial to mesenchymal transition (EMT) to acquir...

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Bibliografiske detaljer
Main Authors: Cimadamore, Flavio, Fishwick, Katherine, Giusto, Elena, Gnedeva, Ksenia, Cattarossi, Giulio, Miller, Amber, Pluchino, Stefano, Brill, Laurence M., Bronner-Fraser, Marianne, Terskikh, Alexey V.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110917/
https://ncbi.nlm.nih.gov/pubmed/21549328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.03.011
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