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Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

Direct control of microRNA (miRNA) expression by oncogenic and tumor suppressor networks results in frequent dysregulation of miRNAs in cancer cells and contributes to tumorigenesis. We previously demonstrated that activation of the c-Myc oncogenic transcription factor (Myc) broadly influences miRNA...

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Bibliografische gegevens
Hoofdauteurs: Chang, Tsung-Cheng, Zeitels, Lauren R., Hwang, Hun-Way, Chivukula, Raghu R., Wentzel, Erik A., Dews, Michael, Jung, Jason, Gao, Ping, Dang, Chi V., Beer, Michael A., Thomas-Tikhonenko, Andrei, Mendell, Joshua T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651245/
https://ncbi.nlm.nih.gov/pubmed/19211792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808300106
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