Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

Direct control of microRNA (miRNA) expression by oncogenic and tumor suppressor networks results in frequent dysregulation of miRNAs in cancer cells and contributes to tumorigenesis. We previously demonstrated that activation of the c-Myc oncogenic transcription factor (Myc) broadly influences miRNA...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Chang, Tsung-Cheng, Zeitels, Lauren R., Hwang, Hun-Way, Chivukula, Raghu R., Wentzel, Erik A., Dews, Michael, Jung, Jason, Gao, Ping, Dang, Chi V., Beer, Michael A., Thomas-Tikhonenko, Andrei, Mendell, Joshua T.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651245/
https://ncbi.nlm.nih.gov/pubmed/19211792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808300106
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