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Shear stress activation of nuclear receptor PXR in endothelial detoxification

Endothelial cells (ECs) are constantly exposed to xenobiotics and endobiotics or their metabolites, which perturb EC function, as well as to shear stress, which plays a crucial role in vascular homeostasis. Pregnane X receptor (PXR) is a nuclear receptor and a key regulator of the detoxification of...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Wang, Xiaohong, Fang, Xi, Zhou, Jing, Chen, Zhen, Zhao, Beilei, Xiao, Lei, Liu, Ao, Li, Yi-Shuan J., Shyy, John Y.-J., Guan, Youfei, Chien, Shu, Wang, Nanping
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740860/
https://ncbi.nlm.nih.gov/pubmed/23878263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312065110
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