Shear stress activation of nuclear receptor PXR in endothelial detoxification

Endothelial cells (ECs) are constantly exposed to xenobiotics and endobiotics or their metabolites, which perturb EC function, as well as to shear stress, which plays a crucial role in vascular homeostasis. Pregnane X receptor (PXR) is a nuclear receptor and a key regulator of the detoxification of...

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Detalhes bibliográficos
Main Authors: Wang, Xiaohong, Fang, Xi, Zhou, Jing, Chen, Zhen, Zhao, Beilei, Xiao, Lei, Liu, Ao, Li, Yi-Shuan J., Shyy, John Y.-J., Guan, Youfei, Chien, Shu, Wang, Nanping
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740860/
https://ncbi.nlm.nih.gov/pubmed/23878263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312065110
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