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Shear Stress Induces Synthetic-to-Contractile Phenotypic Modulation in Smooth Muscle Cells via PPAR-α/δ Activations by Prostacyclin Released by Sheared Endothelial Cells
RATIONALE: Phenotypic modulation of smooth muscle cells (SMCs), which are located in close proximity to endothelial cells (ECs), is critical in regulating vascular function. The role of flow-induced shear stress in the modulation of SMC phenotype has not been well defined. OBJECTIVE: The objective w...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3772782/ https://ncbi.nlm.nih.gov/pubmed/19628794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.193656 |
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