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Single crystal structural and absorption spectral characterizations of nitric oxide synthase complexed with N(ω)-hydroxy-L-arginine and diatomic ligands

The X-ray structures of neuronal nitric oxide synthase (nNOS) with N(ω)-hydroxy-L-arginine (L-NHA) and CO (or NO) bound have been determined at 1.91 to 2.2 Å resolution. Microspectrophotometric techniques confirmed reduced redox state and the status of diatomic ligand complexes during X-ray diffract...

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Detalhes bibliográficos
Main Authors: Doukov, Tzanko, Li, Huiying, Soltis, Michael, Poulos, Thomas L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740733/
https://ncbi.nlm.nih.gov/pubmed/19791770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9009743
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