Wird geladen...

Temperature dependent spin crossover in neuronal nitric oxide synthase bound with the heme-coordinating thioether inhibitors

A series of L-arginine analogue nitric oxide synthase inhibitors with a thioether tail have been shown to form an Fe-S thioether interaction as evidenced by continuous electron density between the Fe and S atoms. Even so, the Fe-S thioether interaction was found to be far less important for inhibito...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Doukov, Tzanko, Li, Huiying, Sharma, Ajay, Martell, Jeffrey D., Soltis, Michael, Silverman, Richard B., Poulos, Thomas L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193996/
https://ncbi.nlm.nih.gov/pubmed/21534614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja201466v
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!