Bioinspired total synthesis of katsumadain A by organocatalytic enantioselective 1,4-conjugate addition

Katsumadain A, a naturally occurring influenza virus neuraminidase (NA) inhibitor, was synthesized by using a bioinspired, organocatalytic enantioselective 1,4-conjugate addition of styryl-2-pyranone with cinnamaldehyde, followed by a tandem Horner–Wadsworth–Emmons/oxa Michael addition.

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Bibliografske podrobnosti
Main Authors: Wang, Yongguang, Bao, Ruiyang, Huang, Shengdian, Tang, Yefeng
Format: Artigo
Jezik:Inglês
Izdano: Beilstein-Institut 2013
Teme:
Letter
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740603/
https://ncbi.nlm.nih.gov/pubmed/23946860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.182
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