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Identification of ROCK1 kinase as a critical regulator of Beclin1 mediated autophagy during metabolic stress
The Ser/Thr Rho kinase 1 (ROCK1) is known to play major roles in a wide range of cellular activities, including those involved in tumor metastasis and apoptosis. Here we identify an indispensable function of ROCK1 in metabolic stress-induced autophagy. Applying a proteomics approach, we characterize...
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| Huvudupphovsmän: | , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740589/ https://ncbi.nlm.nih.gov/pubmed/23877263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3189 |
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