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Backpropagating Action Potentials Enable Detection of Extrasynaptic Glutamate by NMDA Receptors

Synaptic NMDA receptors (NMDARs) are crucial for neural coding and plasticity. However, little is known about the adaptive function of extrasynaptic NMDARs occurring mainly on dendritic shafts. Here, we find that in CA1 pyramidal neurons, backpropagating action potentials (bAPs) recruit shaft NMDARs...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wu, Yu-Wei, Grebenyuk, Sergei, McHugh, Thomas J., Rusakov, Dmitri A., Semyanov, Alexey
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740263/
https://ncbi.nlm.nih.gov/pubmed/22832274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.03.007
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