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Backpropagating Action Potentials Enable Detection of Extrasynaptic Glutamate by NMDA Receptors
Synaptic NMDA receptors (NMDARs) are crucial for neural coding and plasticity. However, little is known about the adaptive function of extrasynaptic NMDARs occurring mainly on dendritic shafts. Here, we find that in CA1 pyramidal neurons, backpropagating action potentials (bAPs) recruit shaft NMDARs...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740263/ https://ncbi.nlm.nih.gov/pubmed/22832274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.03.007 |
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