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Opposing action of conantokin-G on synaptically and extrasynaptically-activated NMDA receptors()

Synaptic and extrasynaptic activation of the N-methyl-D-aspartate receptor (NMDAR) has distinct consequences on cell signaling and neuronal survival. Since conantokin (con)-G antagonism is NR2B-selective, which is the key subunit involved in extrasynaptic activation of the receptor, its ability to s...

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Autori principali: Balsara, Rashna, Li, Neill, Weber-Adrian, Danielle, Huang, Louxiu, Castellino, Francis J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680358/
https://ncbi.nlm.nih.gov/pubmed/22306487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.01.018
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