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Opposing action of conantokin-G on synaptically and extrasynaptically-activated NMDA receptors()
Synaptic and extrasynaptic activation of the N-methyl-D-aspartate receptor (NMDAR) has distinct consequences on cell signaling and neuronal survival. Since conantokin (con)-G antagonism is NR2B-selective, which is the key subunit involved in extrasynaptic activation of the receptor, its ability to s...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3680358/ https://ncbi.nlm.nih.gov/pubmed/22306487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.01.018 |
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