Modulation of extrasynaptic NMDA receptors by synaptic and tonic zinc

Many excitatory synapses contain high levels of mobile zinc within glutamatergic vesicles. Although synaptic zinc and glutamate are coreleased, it is controversial whether zinc diffuses away from the release site or whether it remains bound to presynaptic membranes or proteins after its release. To...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Anderson, Charles T., Radford, Robert J., Zastrow, Melissa L., Zhang, Daniel Y., Apfel, Ulf-Peter, Lippard, Stephen J., Tzounopoulos, Thanos
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443361/
https://ncbi.nlm.nih.gov/pubmed/25947151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503348112
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