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Cell-specific gain modulation by synaptically released zinc in cortical circuits of audition

In many excitatory synapses, mobile zinc is found within glutamatergic vesicles and is coreleased with glutamate. Ex vivo studies established that synaptically released (synaptic) zinc inhibits excitatory neurotransmission at lower frequencies of synaptic activity but enhances steady state synaptic...

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Bibliographic Details
Published in:eLife
Main Authors: Anderson, Charles T, Kumar, Manoj, Xiong, Shanshan, Tzounopoulos, Thanos
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876454/
https://ncbi.nlm.nih.gov/pubmed/28887876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29893
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