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Toll-like Receptor-4 Mediates Neutrophil Sequestration and Lung Injury Induced by Endotoxin and Hyperinflation
OBJECTIVE: Infiltration of polymorphonuclear neutrophils into the lung is an important feature of ventilator-induced lung injury associated with pneumonia, but the mechanisms involved in neutrophil recruitment are poorly understood. Using Toll-like receptor 4 knockout (tl4r(−/−)) mice, we addressed...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3739989/ https://ncbi.nlm.nih.gov/pubmed/19789446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e3181bc7c17 |
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