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Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs

The rapid and selective accumulation of neutrophils into the lungs is thought to underlie the pulmonary failure that leads to sepsis-related death. In this study we investigated whether neutrophil TLR4 is important in LPS-induced pulmonary neutrophil recruitment by creating chimeric mice (transferri...

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Detalhes bibliográficos
Main Authors: Andonegui, Graciela, Bonder, Claudine S., Green, Francis, Mullaly, Sarah C., Zbytnuik, Lori, Raharjo, Eko, Kubes, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152584/
https://ncbi.nlm.nih.gov/pubmed/12671050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316510
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