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AAV-mediated gene targeting methods for human cells

Gene targeting with adeno-associated virus (AAV) vectors has been demonstrated in multiple human cell types, with targeting frequencies ranging from 10(−5) to 10(−2) per infected cell. these targeting frequencies are 1–4 logs higher than those obtained by conventional transfection or electroporation...

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Autors principals: Khan, Iram F, Hirata, Roli K, Russell, David W
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739714/
https://ncbi.nlm.nih.gov/pubmed/21455185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2011.301
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