Engineering of Human Pluripotent Stem Cells by AAV-mediated Gene Targeting

Precise genetic manipulation of human pluripotent stem cells will be required to realize their scientific and therapeutic potential. Here, we show that adeno-associated virus (AAV) gene targeting vectors can be used to genetically engineer human embryonic stem cells (ESCs) and induced pluripotent st...

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Detalhes bibliográficos
Main Authors: Khan, Iram F, Hirata, Roli K, Wang, Pei-Rong, Li, Yi, Kho, Jordan, Nelson, Angel, Huo, Yunwen, Zavaljevski, Maja, Ware, Carol, Russell, David W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889726/
https://ncbi.nlm.nih.gov/pubmed/20407427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.55
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