Trisomy Correction in Down Syndrome Induced Pluripotent Stem Cells

Human trisomies can alter cellular phenotypes and produce congenital abnormalities such as Down syndrome (DS). Here we have generated induced pluripotent stem cells (iPSCs) from DS fibroblasts and introduced a TKNEO transgene into one copy of chromosome 21 by gene targeting. When selecting against T...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, Li B., Chang, Kai-Hsin, Wang, Pei-Rong, Hirata, Roli K., Papayannopoulou, Thalia, Russell, David W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705773/
https://ncbi.nlm.nih.gov/pubmed/23084023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.08.004
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