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Chromosomal position effects on AAV-mediated gene targeting

The effects of chromosomal position and neighboring genomic elements on gene targeting in human cells remain largely unexplored. To study these, we used a shuttle vector system in which murine leukemia virus (MLV)-based proviral targets present at different chromosomal locations and containing mutat...

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Detalhes bibliográficos
Main Authors: Cornea, Anda M., Russell, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887962/
https://ncbi.nlm.nih.gov/pubmed/20185563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq095
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